Antibody-Dependent Cell Mediated Cytotoxicity

Antibody-Dependent Cell Mediated Cytotoxicity (ADCC) is when leukocytes bearing F(c) receptors bind to and destroy […]

Cell-mediated response

Cell-mediated immunity is an immune response that does not involve antibodies but rather involves the […]

Circulation and extravasation

Circulating white blood cells are stimulated to cross out of blood circulation (extravasation) by sets […]

Complement cascade

The complement cascade (aka complement system or just complement) has seven functions -- shown in […]

Cytokine receptors

There are five families of cytokine receptor, described below with their accompanying ligands. Immunoglobulin Superfamily […]

Cytokines

Cytokines (aka monokines or lymphokines) are regulatory proteins which bind specific receptors and have pleiotropic […]

Hypersensitivity

Type 1: Allergy Type I hypersensitivity (most commonly allergies) stem from overproduction of IgE. Thus, […]

Inflammatory response

The inflammatory response is characterized by the following three events Vasodilation. Vasodilation is an increase […]

Major histocompatibility complex

The major histocompatibility complex (MHC, or MHC complex) is present in all vertebrates, and is […]

Nuclear Factor κB

Nuclear Factor Kappa B (NF-κB) is a widespread transcription factor that activates various thymocyte and […]

Pattern-Recognition Receptors

Cells of the innate immune system recognize non-self cells by detecting structures unique to microbial […]

Phagocytosis

Bound pathogen is surrounded by a membrane, forming the phagosome which becomes acidified. Lycososomes containing […]

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