| Term | Overview |
|---|---|
| Anthroponosis | Disease with humans as only vertebrate hosts. |
| Zoonosis | Disease transmitted among wild animals (reservoir hosts) and humans. |
| Reservoir Host | Wild animal that maintains infection in nature. |
| Procyclic | Related to the beginning of the parasite’s life cycle. |
| Metacyclic | Related to the infective stage of the parasite’s life cycle. |
| VSG | Variable surface glycoprotein |
| ESAG | Expression site associated glyocoprotein |
| COG | A bluster of orthologous genes (COG). |
| 3-Way COG | A 3-Way COG is orthologous between three species. |
| 2-Way COG | A 2-way COG is orthologous between two species. . |
| Synteny | A phenomenon where a COG consists of five or more genes. |
Virulence factors are cellular properties which promote pathogenesis. Without these virulence factors, pathogenesis is attenuated or eliminated. These virulence factors can be:
| Factor | Overview |
|---|---|
| Adherence | Colonization and contact.. |
| Invasins | Tissue and cell invasion. |
| Toxins | Motility and chemotaxis. |
| Nutrition | Compete for nutrients. |
| Evasion | Evasion and suppression of immune response. |
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