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Galectin


Written by      First published December 2, 2009      Last modified August 24, 2011

Mammalian galectins bind carbohydrates, preferring poly-N-acetyl lactosamine (Galβ1→4GlcNAcβ1). The three structural groups are:

Proto Galectin

Galectin-1,2,5,7,10. Cross-link homologous carbohydrate ligands.

Chimera Galectin

Galectin-3. Cross-links carbohydrate and non-carbohydrate ligands.

Tandem Repeat Galectin

Galectin-4,6,8,9. Cross-link two distinct carbohydrate ligands.


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