Self-Splicing IntronsComments
parentRNA processing
siblings5' mRNA CapAlternative splicingGuide RNA (gRNA)PolyadenylationRNA splicingSpliceosomeSplicingUridine Deletion/Insertion RNA Editing

Self-Splicing Introns

Some mitochondrial, protist and archaeal genes have autocatalytic self-splicing introns (as opposed to nuclear spliceosome-dependent introns). These introns fold into specific secondary and tertiary structures that catalyze their own excision, without proteins. There are two families of these introns -- Group I and and Group II -- and Group II autocatalytic introns are thought to operate with a similar mechanism to the spliceosome catalytic center.