Uniparental DisomyComments
parentGenetic disease
siblingsAndrogen InsensitivityBalanced RearrangementCancer geneticsChromosome Number AbnormalitiesCystic FibrosisDown SyndromeDuchenne Muscular DystrophyFragile X SyndromeHemoglobinopathyHuntington DiseaseHurler SyndromeHyperphenylalaninemiamRNA Splicing AberrationsNondisjunctionPenis-At-Twelve SyndromeRelative RiskSickle Cell DiseaseSpinal Muscular AtrophyTay-Sachs DiseaseThalassemiaTriplet Repeat ExpansionsTrisomy 13Trisomy 18Unbalanced Rearrangement

Uniparental Disomy

Uniparental disomy of a chromosome may arise via confined placental mosaicism, a condition where a trisomic fetus loses one of its trisomic chromosomes. For that chromosome pair, the fetus has only alleles from one parent remaining; however, the placenta is still trisomic.