SRY
By Levi Clancy for Student Reader on
updated
- Developmental Biology
- Genetics and Genomics
- Central dogma
- Chi-squared test
- Darwinian Evolution
- Evolutionary agents
- Gene
- Gene regulation
- Genetic and phenotypic variation
- Genetic code
- Genetic disease
- Genetics and Genomics Questions
- Genomic imprinting
- Genomics
- Hardy-Weinberg equilibrium
- Homeodomain
- Human genetics
- Insertion sequence elements
- LOD Score
- Lac Operon
- Linkage analysis
- Mendel's Laws of Genetics
- Mutation
- Polymorphism
- SRY
- Sex
- Reproductive system
Also known as the testes-determining gene or sex-determining region on the Y chromosome, SRY is a gene located on the short arm of the Y chromosome and encodes a DNA-binding transcription factor known as testes-determining factor (TDF) early (and briefly) in development. Although SRY does not determine sex in all cases -- it is not present in 10% of unambiguous XX males -- it is a key instrument in the concert of sex determination.