Cytokine receptors
By Levi Clancy for Student Reader on
updated
There are five families of cytokine receptor, described below with their accompanying ligands.
| Immunoglobulin Superfamily Receptors | IL-1, M-CSF, C-Kit |
|---|---|
| Class I Cytokine Receptors | IL-2,3,4,5,6,7,9,11,13,15, GM-CSF, G-CSF, OSM, LIF, CNTF, Growth Hormone, Prolactin |
| Class II Cytokine Receptors | IFNα, IFNβ, IFNγ, IL-10 |
| Tumor Necrosis Factor (TNF) Receptors | TNFα, TNFβ, CD40, Nerve Growth Factor (NGF), FAS |
| Chemokine Receptors | IL-8, RANTES, MIP-1, PF4, MCAF, NAP-2, SDF-1 |
A thoroughly-studied disease of cytokine receptors is SCID, a genetic disorder which has helped reveal the roles that cytokines play.