By Levi Clancy for Student Reader on
There are five families of cytokine receptor, described below with their accompanying ligands.
|Immunoglobulin Superfamily Receptors||IL-1, M-CSF, C-Kit|
|Class I Cytokine Receptors||IL-2,3,4,5,6,7,9,11,13,15, GM-CSF, G-CSF, OSM, LIF, CNTF, Growth Hormone, Prolactin|
|Class II Cytokine Receptors||IFNα, IFNβ, IFNγ, IL-10|
|Tumor Necrosis Factor (TNF) Receptors||TNFα, TNFβ, CD40, Nerve Growth Factor (NGF), FAS|
|Chemokine Receptors||IL-8, RANTES, MIP-1, PF4, MCAF, NAP-2, SDF-1|
A thoroughly-studied disease of cytokine receptors is SCID, a genetic disorder which has helped reveal the roles that cytokines play.