Nuclear Factor κBComments
parentImmunological Pathways
siblingsAntibody-Dependent Cell Mediated CytotoxicityCell-mediated immune responseCirculation and extravasationComplement cascadeCytokine receptorsCytokinesHypersensitivityInflammatory responseMajor histocompatibility complexPattern-Recognition ReceptorsPhagocytosis

Nuclear Factor κB

Nuclear Factor Kappa B (NF-κB) is a widespread transcription factor that activates various thymocyte and b lymphocyte genes. It is inhibited by inhibitor of κB (IκB). In turn, IκB is inactivated by inhibitor of κB kinase (IKK) via phosphorylation.