The Sodium/Potassium Pump puts Na+ outside the cell and K+ inside the cell.
- 3Na+ mols inside bind to receptor
- This stimulates phosphorylation of receptor by ATP.
- This alters receptor shape, shape change dumps Na+ onto inside.
- Open receptors bind 2K+ ions outside.
- K+ binding triggers phosphate release.
- This restores original conformation.
- K+ released inside, NA+ sites become available.
- Net: 1 ATP lost; 3 Na+ outside; 2 K+ inside.