Axonal pathfinding

An axon often has to navigate great distance to reach its target cell (ie, another […]

Axonal pathfinding and neural crest cells

Neural crest cells form at the anterior end of the neural plate, at the border […]

Brain and spinal cord

The Neural Tube Dorsal-Ventral Axes and the Role of Shh Starting at the ventral end, […]

Brain Development

The brain develops from the neural tube. Before even fully developing at the posterior, the […]

Cytoplasmic Body Plan Determinants

Localized mRNAs are critical early in embryogenesis to establish axes, and have been identified via […]

Ectodermal appendages

What Are Ectodermal Placodes? What Sensory Organs Do They Form? A placode is a thickened […]

Eye development

1st InductionSpecific positions along the anterior-posterior axis of the archenteron (cells arising from the organizer […]

Limb development

What are the signaling centers controlling limb bud formation? Apical Ectodermal Ridge The Apical Ectodermal […]

Liver development

Similar to the tracheal and pancreatic buds and their branches, the hepatic (liver) bud is […]

Lung development

The lung bud (aka tracheal bud) evaginates from the ventral foregut endoderm. The lung bud […]


Following gastrulation, organogenesis (formation of organs) begins and part of this is neurulation, the formation […]

Pancreas development

Similar to the tracheal and hepatic buds and their branches, the peancreatic bud is an […]

Sonic hedgehog

Expression of vertebrate Sonic hedgehog protein is extremely localized to the notochord and spinal cord […]

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